“An Update Review on Recent Advancements in Multiple Emulsion”
- August 27, 2018
- Posted by: RSIS
- Category: Pharmacy
International Journal of Research and Scientific Innovation (IJRSI) | Volume V, Issue VIII, August 2018 | ISSN 2321–2705
Sarika S. Lokhande*, Namita N. Phalke*, Vijay N. Raje, Savita S. More
GES College of Pharmacy, Limb, Satara, Maharashtra, India
*Corresponding Author- Sarika S. Lokhande, Namita N. Phalke
Abstract:-Emulsions are scatter systems of two immiscible or inadequately miscible liquid phases. Emulsion can be classified as simple oil-in-water (O/W) or water-in-oil (W/O) emulsions and multiple water-in oil-in-water (W/O/W) or oil-in-water-in-oil (O/W/O) emulsions. W/O/W emulsions had been used as drug delivery system (DDS).Preparation of mono dispersed multiple emulsion is important in DDS to improve their stability and to make possible control of their properties. This review described five methods to prepare multiple emulsions viz. two-step emulsification method, modified two-step emulsification method, phase inversion method & membrane emulsification. With the progression in techniques for preparation, stabilization and rheological characterization of multiple emulsions, it will be able to provide a new carrier system for drugs, cosmetics and pharmaceutical agents.
Keywords: Multiple Emulsions, o/w/o & w/o/w, Emulsifying agent, Stability of Emulsions
Emulsions may be described as heterogeneous systems, where one immiscible liquid is dispersed in the form of droplets and stabilized by a third constituent called emulsifying agent. These two liquids are also chemically nonreactive and form the systems that are characterized by a low thermodynamically stability.
Based on their formation, emulsions can be divided into:
1. Simple Emulsion and
2. Multiple Emulsions.